S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Msn2p	YGR088W	PubMed Martínez-Pastor MT et al., The EMBO journal, 1996 May 1;15(9):2227-35	Indirect	Northern blot - wt vs TF overexpression	Positive	S288c	Unstressed log-phase growth (control)	S medium	N/A
		PubMed Schmitt AP et al., Proceedings of the National Academy of Sciences of the United States of America, 1996 Jun 11;93(12):5777-82	Indirect	Northern blot - wt vs TF overexpression	Positive	S288c	Stress	Methylmethane sulfonate stress	N/A
		PubMed McBride HJ et al., The Journal of biological chemistry, 1999 Jul 23;274(30):21029-36	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Stress	Heat Shock 30ºC - 37ºC 20min	N/A
		PubMed Boy-Marcotte E et al., Molecular microbiology, 1999 Jul;33(2):274-83	Indirect	Proteomics - wt vs TF mutant	Positive	W303-A	Stress	Heat-shock: Exponential-phase cells shifted from 25C to 38C	N/A
		PubMed Garcia SC et al., FEMS microbiology letters, 2000 Mar 15;184(2):219-24	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Stress	YPD + 0,5M NaCl	N/A
		PubMed Epstein CB et al., Molecular biology of the cell, 2001 Feb;12(2):297-308	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Stress	YPD medium + 0,05M succinic acid, pH 4,0	N/A
		PubMed Amorós M et al., Molecular microbiology, 2001 Mar;39(6):1523-32	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Carbon source quality/availability	Carbon source starvation	N/A
			Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Stress	Heat shock	N/A
			Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Stress	Osmotic stress	N/A
			Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Stress	oxidative stress	N/A
		PubMed Hasan R et al., Molecular microbiology, 2002 Jul;45(1):233-41	Indirect	Proteomics - wt vs TF mutant	Positive	YPH98	Stress	Oxidative stess; cells grown in YNB medium to exponential phase exposed to 0.5 mM H2O2 for 30 min	N/A
			Indirect	2D electrophoresis (WT vs msn2DELTAmsn4DELTAyap1DELTA triple mutant)	Positive	YPH98	Stress	Oxidative stess; cells grown in YNB medium to exponential phase exposed to 0.5 mM H2O2 for 30 min	N/A
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Yamamoto A et al., The Journal of biological chemistry, 2005 Mar 25;280(12):11911-9	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Stress	YPD medium 39ºC (heat shock)	N/A
		PubMed Lai LC et al., Molecular and cellular biology, 2005 May;25(10):4075-91	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Oxygen availability	SSGal-TEA medium + anaerobiosis (0,08 generations)	N/A
		PubMed Bourges I et al., The Journal of biological chemistry, 2005 Aug 19;280(33):29743-9	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Stress	Myxothiazol - Cells were cultivated in YPGal for 7 h and 50 min. Acetoin or acetaldehyde were added at concentrations of 10 mM, and the cells were incubated for 10 min. 8 M myxothiazol was then added, and the cells were incubated for another 10 min	N/A
		PubMed Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF overexpression	Positive	N/A	Carbon source quality/availability	Cells grown in selective medium supplemented with 2% raffinose before induction with 2% galactose for 3 h	N/A
		PubMed Eastmond DL et al., The Journal of biological chemistry, 2006 Oct 27;281(43):32909-21	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303-1A	Stress	Cells grown in YPAD at 30.C to mid-log phase (A600 of 0.5) submitted to heat-shock (37.C, 15 min)	N/A
		PubMed Yamamoto A et al., Eukaryotic cell, 2007 Aug;6(8):1373-9	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Stress	Diamide	N/A
		PubMed Capaldi AP et al., Nature genetics, 2008 Nov;40(11):1300-6	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Stress	YPD medium containing 0,8M glucose (glucose "osmotic" stress)	N/A
		PubMed Watanabe D et al., Applied and environmental microbiology, 2011 Feb;77(3):934-41	Indirect	RT-PCR - wt vs TF mutant	Positive	S288c	Complex industrial media	Sake mash on day 5	N/A
		PubMed Kim HS et al., Applied microbiology and biotechnology, 2011 Aug;91(4):1159-72	Indirect	Northern blot - wt vs TF mutant	Negative	S288c	Stress	YPD+10%ethanol, 30 min	N/A
		PubMed Solé C et al., The EMBO journal, 2011 Jul 8;30(16):3274-84	Direct	ChIP	N/A	S288c	Stress	0,4M NaCl	N/A
		PubMed Huebert DJ et al., Molecular and cellular biology, 2012 May;32(9):1645-53	Direct	Chip-on-chip	N/A	S288c	Stress	H2O2 treatment	N/A
		PubMed Sasano Y et al., Bioscience, biotechnology, and biochemistry, 2012;76(3):624-7	Direct	RT-PCR - wt vs mutant promoter sequence	Positive	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Stewart-Ornstein J et al., Current biology : CB, 2013 Dec 2;23(23):2336-45	Indirect	GFP - wt vs TF overexpression	Positive	S288c	Stress	Estradiol induced	N/A
		PubMed Elfving N et al., Nucleic acids research, 2014 May;42(9):5468-82	Indirect	Microarray analysis - wt vs TF overexpression	Positive	S288c	Unstressed log-phase growth (control)	SD + glucose + estradiol induction	N/A
		PubMed Cho BR et al., Biochimica et biophysica acta. Gene regulatory mechanisms, 2017 Jun;1860(6):695-704	Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741	Stress	1Â mM H2O2	N/A
			Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741	Carbon source quality/availability	2% lactic acid	N/A
			Indirect	RT-PCR - wt vs TF mutant	Positive	BY4741	Unstressed log-phase growth (control)	2% glucose	N/A
		PubMed Rajvanshi PK et al., The Journal of biological chemistry, 2017 Nov 10;292(45):18628-18643	Direct	ChIP	N/A	BY4741	Carbon source quality/availability	2% or 6% glucose, stationary phase	N/A
		PubMed Kuang Z et al., eLife, 2017 Sep 26;6():Kuang Z et al., eLife, 2017 Sep 26;6():	Direct	ChIP-seq	N/A	BY5764	Unstressed log-phase growth (control)	YPD 30.C	N/A
		PubMed Nakazawa N et al., The Journal of general and applied microbiology, 2018 Sep 27;64(4):149-157	Indirect	Northern blot - wt vs TF mutant	Positive	MCY3605	Stress	H2O2 stress	N/A
			Indirect	Northern blot - wt vs TF mutant	Positive	Shirakami kodama yeast (S. cerevisiae) IB1306 MATalpha ho	Unstressed log-phase growth (control)	Cells grown in supplemented synthetic medium (SD, 0.67% yeast nitrogen base without amino acids, 2% glucose, and a supplement with amino acids).	N/A
			Indirect	Northern blot - wt vs TF mutant	Positive	Shirakami kodama yeast (S. cerevisiae) IB1306 MATalpha ho	Stress	Cells grown in supplemented synthetic medium (SD, 0.67% yeast nitrogen base without amino acids, 2% glucose, and a supplement with amino acids) treated with 0.3 mM H2O2 for 30 min at 30 .C (oxidative stress)	N/A
			Indirect	Northern blot - wt vs TF mutant	Positive	MCY3605	Stress	synthetic medium containing uracil with 0.3 mM H2O2 for 30 min	N/A
		PubMed Pfanzagl V et al., Molecular biology of the cell, 2018 Nov 15;29(23):2848-2862	Indirect	Microarray analysis - wt vs TF mutant	Positive	W303-1A	Unstressed log-phase growth (control)	YPD 30.C	N/A
		PubMed Sweeney K et al., Cell reports, 2023 May 30;42(5):112426	Indirect	mCitrine reporter - wt vs TF light activation	Positive	S288C	Unstressed log-phase growth (control)	LFM medium + light	N/A
		PubMed Watanabe D et al., NPJ science of food, 2023 Jul 21;7(1):37	Indirect	RT-PCR - wt vs TF double mutant	Positive	BY4741	Carbon source quality/availability	YPD 20% glucose medium (fermentation stationary phase)	N/A
		PubMed Duy DL et al., Nucleic acids research, 2023 Oct 13;51(18):9643-9657	Direct	ChIP	N/A	YPH45	Carbon source quality/availability	SC Glycerol medium	N/A
		PubMed Mindel V et al., Nucleic acids research, 2024 Mar 21;52(5):2260-2272	Direct	ChEC-seq	N/A	BY4741	Unstressed log-phase growth (control)	SD medium + Mutated Msn2	N/A