Yeastract
YEASTRACT+ INESC-ID IST IBB
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Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.
Transcription
Factor
Target
ORF/Genes
References Evidence
Code
Evidence
Experiment
Association
Type
Strain Environmental
Group
Environmental
Condition
Log2FC
Rph1p YJL107C PubMed external link Liang CY et al., Molecular biology of the cell, 2013 Oct;24(20):3251-62Liang CY et al., Molecular biology of the cell, 2013 Oct;24(20):3251-62 Indirect Microarray analysis - wt vs TF mutant Positive S288c Unstressed log-phase growth (control) YPD 30.C N/A
PubMed external link Shu WJ et al., Nucleic acids research, 2020 Sep 4;48(15):8360-8373Shu WJ et al., Nucleic acids research, 2020 Sep 4;48(15):8360-8373 Indirect RNA-seq analysis - WT vs TF Deletion Positive BY4741 Carbon source quality/availability Steady state carbon-limited chemostat cultures operated at a dilution rate of 0.05 per h by continuous addition of medium (feed concentration of glucose, 10 g/liter) at 30°C. pH controlled at 5, aerated with 0.5 volume of air/volume of liquid/min and with 800 rpm agitation. Transcription factor gene deletion. 0.529587472915699
Indirect RNA-seq analysis - WT vs TF Deletion Positive BY4741 Carbon source quality/availability Ethanol medium - Overexpression media lacked leucine to ensure plasmid selection. The cultures grown for 70 h in ethanol medium were diluted twice with a fresh medium to ensure continuous growth. 0.926592152653692
Indirect RNA-seq analysis - WT vs TF Deletion Positive BY4741 Unstressed log-phase growth (control) Grown in YPD to OD600 of 0.8 at 30 ºC. Transcription factor gene deletion. 0.529587472915699
Indirect RNA-seq analysis - WT vs TF Deletion Positive BY4741 Nitrogen source quality/availability Grown in YPD to OD600 of 0.8 at 30 ºC. Treated with rapamycin for 2h (100 nM). Transcription factor gene deletion. 0.926592152653692
PubMed external link Fang W et al., Cell reports, 2022 Apr 12;39(2):110672Fang W et al., Cell reports, 2022 Apr 12;39(2):110672 Indirect RNA-seq analysis - WT vs TF Deletion Positive CEN.PK Carbon source quality/availability Yeast cells grown to log phase in YPL medium from 0.1 OD with switch to SL minimal medium for 1h. Transcription factor gene deletion. 0.659958039059791
Indirect RNA-seq analysis - WT vs TF Deletion Negative CEN.PK Carbon source quality/availability Yeast cells grown to log phase in YPL medium from 0.1 OD with switch to SL minimal medium for 3h. Transcription factor gene deletion. -0.775596141770182
PubMed external link Glazier VE et al., mBio, 2023 Oct 31;14(5):e0152123Glazier VE et al., mBio, 2023 Oct 31;14(5):e0152123 Indirect RNA-seq analysis - WT vs TF Deletion Positive BY4741 Unstressed log-phase growth (control) Cultured in minimal medium (1.7 g/L YNB, 5 g/L ammonium sulfate, 20 g/L glucose, 80 mg/L histidine, 80 mg/L methionine, 80 mg/L uracil and 240 mg/L leucine) with 200 rpm orbital shaking at 30°C, pH 5.5, until the mid-exponential phase (OD600 = 0.6). Transcription factor gene deletion. 1.85707482929138