S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Ume6p	YML058W	PubMed Lardenois A et al., Molecular genetics and genomics : MGG, 2015 Oct;290(5):2031-46	Indirect	Microarray analysis - WT vs TF Deletion	Negative	SK1	Cell cycle/morphology	Grown in sporulation medium (SPII for 10 h) under standard conditions. Transcription factor gene deletion.	-1.109735
			Indirect	Microarray analysis - WT vs TF Deletion	Positive	SK1	Cell cycle/morphology	Grown in sporulation medium (SPII for 4 h) under standard conditions. Transcription factor gene deletion.	0.575573
			Indirect	Microarray analysis - WT vs TF Deletion	Negative	SK1	Cell cycle/morphology	Grown in sporulation medium (SPII for 8 h) under standard conditions. Transcription factor gene deletion.	-1.062579
			Indirect	Microarray analysis - WT vs TF Deletion	Negative	SK1	Carbon source quality/availability	Grown in rich media with acetate (YPA) under standard conditions. Transcription factor gene deletion.	-0.517181
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	Unstressed log-phase growth (control)	YPD medium, 25.C	N/A
		PubMed Harris A et al., Genetics, 2023 Oct 4;225(2):	Indirect	RNA-seq analysis - WT vs TF Under-expression	Positive	SK1	Unstressed log-phase growth (control)	Mitotic, 0min: Cells were in mitotic, log-phase growth. They were grown in YPD (1% yeast extract, 2% peptone, 2% dextrose, 22.4 mg/L uracil, 80 mg/L tryptophan) for ~24 h to saturation, then back-diluted into fresh YPD to OD600 = 0.2 and grown ~3 h to log phase (OD600 ≥ 0.5). Once in log phase, β-estradiol (40 nM) was added, followed 30 min later by auxin (200 µM) at t=0min. Sampled at 0 min.	0.29353
			Indirect	RNA-seq analysis - WT vs TF Under-expression	Positive	SK1	Unstressed log-phase growth (control)	Mitotic, 15min: Cells were in mitotic, log-phase growth. They were grown in YPD (1% yeast extract, 2% peptone, 2% dextrose, 22.4 mg/L uracil, 80 mg/L tryptophan) for ~24 h to saturation, then back-diluted into fresh YPD to OD600 = 0.2 and grown ~3 h to log phase (OD600 ≥ 0.5). Once in log phase, β-estradiol (40 nM) was added, followed 30 min later by auxin (200 µM) at t=0min. Sampled at 15 min.	0.378986
			Indirect	RNA-seq analysis - WT vs TF Under-expression	Positive	SK1	Unstressed log-phase growth (control)	Mitotic, 60min: Cells were in mitotic, log-phase growth. They were grown in YPD (1% yeast extract, 2% peptone, 2% dextrose, 22.4 mg/L uracil, 80 mg/L tryptophan) for ~24 h to saturation, then back-diluted into fresh YPD to OD600 = 0.2 and grown ~3 h to log phase (OD600 ≥ 0.5). Once in log phase, β-estradiol (40 nM) was added, followed 30 min later by auxin (200 µM) at t=0min. Sampled at 60 min.	0.260555