S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition	Log2FC
Rap1p	YML058W-A	PubMed Alenquer M et al., FEMS yeast research, 2006 Dec;6(8):1130-9	Indirect	Microarray analysis - WT vs TF Deletion	Positive	W303a	Grown in complete synthetic medium (CSM) when selection was required, or in rich medium (YPD) at 30°C. Temperature shift experiment: exponentially growing yeast cells grown in YPD (A600 = 0.8 − 1.2) at 37°C for 1 h. Transcription factor gene deletion.	2.20575767
		PubMed Tomar RS et al., The EMBO journal, 2008 Jun 4;27(11):1575-84	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Methylmethane sulfonate stress	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Negative	BY4741; S288C; R1158	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	-0.87250298363453
		PubMed Byun JY et al., Microbial cell factories, 2025 Feb 24;24(1):47	Indirect	RNA-seq - wt vs TF overexpression	Negative	CEN.PK2-1D	YPD medium (15h) (diauxic shift)	-2.23125110714436
			Indirect	RNA-seq - wt vs TF overexpression	Negative	CEN.PK2-1D	YPD medium (36h) (post-diauxic shift)	-2.70966919192581
			Indirect	RNA-seq analysis - TF Over-expression vs WT	Negative	cen.pk-2-1C	RNA extraction at 15h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase.	-4.69540989786243
			Indirect	RNA-seq analysis - TF Over-expression vs WT	Negative	cen.pk-2-1C	RNA extraction at 36h. Medium: YPD (1% yeast extract, 2% peptone, 2% glucose) or synthetic complete (SC) medium supplemented as required for auxotrophic markers. Temperature: 30°C, aerobic shaking. Growth phase: exponential or stationary phase.	-6.54171628953846