S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Swi4p	YMR199W	PubMed Dirick L et al., Nature, 1992 Jun 11;357(6378):508-13	N/A		N/A	S288c	N/A	N/A	N/A
		PubMed Ogas J et al., Cell, 1991 Sep 6;66(5):1015-26	N/A		N/A	S288c	N/A	N/A	N/A
		PubMed Nasmyth K et al., Cell, 1991 Sep 6;66(5):995-1013	N/A		N/A	S288c	N/A	N/A	N/A
		PubMed Wittenberg C et al., Cell, 1990 Jul 27;62(2):225-37	N/A		N/A	S288c	N/A	N/A	N/A
		PubMed Toone WM et al., The EMBO journal, 1995 Dec 1;14(23):5824-32	Indirect	Northern blot - wt vs TF mutant	Positive	W303	Stress	SC medium 37.C	N/A
		PubMed Partridge JF et al., The Journal of biological chemistry, 1997 Apr 4;272(14):9071-7	Indirect	lacZ - wt vs TF mutant	Positive	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Iyer VR et al., Nature, 2001 Jan 25;409(6819):533-8	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Simon I et al., Cell, 2001 Sep 21;106(6):697-708	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Lee TI et al., Science (New York, N.Y.), 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Harbison CT et al., Nature, 2004 Sep 2;431(7004):99-104	Direct	Chip-on-chip	N/A	S288c	Unstressed log-phase growth (control)	YPD medium; mid-log phase	N/A
		PubMed Bean JM et al., Genetics, 2005 Sep;171(1):49-61	Indirect	Northern blot - wt vs TF mutant	Positive	S288c	Cell cycle/morphology	Expression along cell cycle	N/A
		PubMed Workman CT et al., Science (New York, N.Y.), 2006 May 19;312(5776):1054-9	Direct	Chip-on-chip	N/A	S288c	N/A	N/A	N/A
		PubMed Chua G et al., Proceedings of the National Academy of Sciences of the United States of America, 2006 Aug 8;103(32):12045-50	Indirect	Microarray analysis - wt vs TF mutant	Positive	N/A	Unstressed log-phase growth (control)	Cells grown in synthetic medium supplemented with 2% dextrose	N/A
		PubMed Badis G et al., Molecular cell, 2008 Dec 26;32(6):878-87	Direct	ChIP	N/A	S288c	N/A	N/A	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	0.62180283313215
		PubMed Hendler A et al., PLoS genetics, 2017 May;13(5):e1006778	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	15Daub	Unstressed log-phase growth (control)	Yeast strains were grown in rich medium at 30°C to an optical density at 600 nm (OD600) of 0.5.	-0.350259612324637
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	15Daub	Unstressed log-phase growth (control)	Yeast growth media (yeast-peptone-dextrose [YPD], yeast-peptone-acetate, and synthetic complete) were of standard composition	2.46989901576113
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	15Daub	Cell cycle/morphology	Cells were grown in 7 ml of SC over-night at 30°C. Cells were synchronized by alpha factor arrest and release and immediately collected. Transcription factor gene deletion.	-0.350259612324637
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	15Daub	Cell cycle/morphology	Cells were grown in 7 ml of SC over-night at 30°C. Cells were synchronized by alpha factor arrest and release and after 30 minutes they were collected. Transcription factor gene deletion.	2.46989901576113
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	Unstressed log-phase growth (control)	YPD medium, 25.C	N/A