S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition	Log2FC
Pho4p	YOL016C	PubMed Ogawa N et al., Molecular biology of the cell, 2000 Dec;11(12):4309-21	Indirect	Microarray analysis - wt vs TF mutant	Positive	S288c	Exponential phase cells cultivated in YPD	N/A
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Positive	BY4741; S288C; R1158	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	1.2501275939686
		PubMed He BZ et al., eLife, 2017 May 9;6():He BZ et al., eLife, 2017 May 9;6():	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	K699	100 ml of cell culture grown to OD600nm (600 nm) of 1.5.	0.402222044096164
			Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	K699	Grown in phosphate-free SC medium (Phosphate starvation) at 30°C with shaking. All transcriptional profiling experiments were done in the pho80∆ background. Transcription factor gene deletion.	0.402222044096164
		PubMed van Heusden GPH, Genomics, 2023 Sep;115(5):110672	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	BY4741	Grown overnight at 30 °C in phosphate-free YNB medium supplemented with 7.2 mM potassium phosphate (pH 5.8), 20 mg/L histidine, leucine, methionine, and uracil, and 50 mM KCl, then used to inoculate 50 mL cultures at OD620 = 0.1 and grown at 30 °C, 180 rpm to OD620 = 0.5. Transcription factor gene deletion.	1.04119289028739
		PubMed Jiang L et al., Biochimica et biophysica acta. Gene regulatory mechanisms, 2025 Dec;1868(4):195107	Indirect	Beta-gal - wt vs TF mutant	Positive	BY4743	YPD medium	N/A
			Indirect	Beta-gal - wt vs TF mutant	Positive	BY4743	YPD medium + 0.2M CaCl2 (calcium stress)	N/A