S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Group	Environmental Condition	Log2FC
Rph1p	YOR215C	PubMed Cipollina C et al., Microbiology (Reading, England), 2008 Jan;154(Pt 1):337-346	Indirect	Microarray analysis - WT vs TF Deletion	Negative	SLY34	Unstressed log-phase growth (control)	Grown in rich medium (YPD) at 30 °C to log phase. Transcription factor gene deletion.	-0.349235
		PubMed Reimand J et al., Nucleic acids research, 2010 Aug;38(14):4768-77	Indirect	Microarray analysis - WT vs TF Deletion	Negative	BY4741; S288C; R1158	Unstressed log-phase growth (control)	Standard YPD conditions Dataset ewxtracted from The Longhorn Array Database (LAD). Transcription factor gene deletion.	-0.4970823490964
		PubMed Shu WJ et al., Nucleic acids research, 2020 Sep 4;48(15):8360-8373	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Carbon source quality/availability	Steady state carbon-limited chemostat cultures operated at a dilution rate of 0.05 per h by continuous addition of medium (feed concentration of glucose, 10 g/liter) at 30°C. pH controlled at 5, aerated with 0.5 volume of air/volume of liquid/min and with 800 rpm agitation. Transcription factor gene deletion.	-0.442236155281335
			Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Unstressed log-phase growth (control)	Grown in YPD to OD600 of 0.8 at 30 ºC. Transcription factor gene deletion.	-0.442236155281335
		PubMed Fang W et al., Cell reports, 2022 Apr 12;39(2):110672	Indirect	RNA-seq analysis - WT vs TF Deletion	Positive	CEN.PK	Carbon source quality/availability	Yeast cells grown to log phase in YPL medium from 0.1 OD with switch to SL minimal medium for 3h. Transcription factor gene deletion.	0.291104116587457
		PubMed Glazier VE et al., mBio, 2023 Oct 31;14(5):e0152123	Indirect	RNA-seq analysis - WT vs TF Deletion	Negative	BY4741	Unstressed log-phase growth (control)	Cultured in minimal medium (1.7 g/L YNB, 5 g/L ammonium sulfate, 20 g/L glucose, 80 mg/L histidine, 80 mg/L methionine, 80 mg/L uracil and 240 mg/L leucine) with 200 rpm orbital shaking at 30°C, pH 5.5, until the mid-exponential phase (OD600 = 0.6). Transcription factor gene deletion.	-0.680290476835062